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. 2021 Feb 1;23(4):245. doi: 10.3892/mmr.2021.11884

Figure 4.

Figure 4.

Exosomal microRNA-17-5p promotes the proliferation and migration of SH-SY5Y cells via inhibition of PTEN and activation of the PI3K/Akt signaling pathway. (A) PTEN, Akt and p-Akt protein expression in SH-SY5Y cells co-cultured with exosomes were measured using western blotting. (B) Cell proliferation was determined using a Cell Counting Kit-8 assay. (C) Cell migration was evaluated via a Transwell assay. *P<0.05, **P<0.01 and ***P<0.001 vs. untreated SH-SY5Y cells. p-, phosphorylated.