Table 1.
Baseline characteristics according to quartiles of baseline TyG index
| Variable | Total | TyG index | P value | |||
|---|---|---|---|---|---|---|
| Quartile 1 (3.61–8.18) | Quartile 2 (8.18–8.57) | Quartile 3 (8.57–9.05) | Quartile 4 (9.05–12.50) | |||
| Participants, n | 97,653 | 24,412 | 24,414 | 24,415 | 24,412 | |
| Age, years | 51.67 (43.53–58.97) | 50.62 (41.69–58.57) | 51.68 (43.52–58.97) | 52.19 (44.13–59.44) | 52.05 (44.33–58.74) | < 0.001 |
| Male, n (%) | 77,748 (79.62) | 18,013 (73.79) | 19,350 (79.26) | 19,839 (81.26) | 20,546 (84.16) | < 0.001 |
| High school or above, n (%) | 19,064 (20.21) | 5751 (24.50) | 4556 (19.23) | 4526 (19.21) | 4231 (17.94) | < 0.001 |
| Income > 800 Renminbi/month, n (%) | 13,466 (14.29) | 3641 (15.52) | 3172 (13.40) | 3315 (14.07) | 3338 (14.16) | < 0.001 |
| Body mass index, kg/m2 | 24.84 (22.60–27.22) | 23.14 (21.11–25.32) | 24.44 (22.39–26.64) | 25.43 (23.41–27.66) | 26.30 (24.22–28.41) | < 0.001 |
| Systolic blood pressure, mm Hg | 130.00 (119.30–140.70) | 120.00 (110.00–135.00) | 129.30 (116.70–140.00) | 130.00 (120.00–143.30) | 131.30 (120.00–150.00) | < 0.001 |
| Diastolic blood pressure, mm Hg | 80.00 (78.70–90.00) | 80.00 (70.70–85.00) | 80.00 (77.30–90.00) | 80.70 (79.30–90.00) | 85.00 (80.00–92.00) | < 0.001 |
| Current smoker, n (%) | 32,577 (34.26) | 7876 (33.34) | 7615 (31.94) | 8160 (34.29) | 8926 (37.47) | < 0.001 |
| Current alcohol use, n (%) | 35,613 (37.44) | 8839 (37.40) | 8309 (34.84) | 8867 (37.25) | 9598 (40.28) | < 0.001 |
| Active physical activity, n (%) | 85,899 (91.27) | 21,392 (91.35) | 21,682 (91.75) | 21,366 (90.82) | 21,459 (91.16) | 0.004 |
| Myocardial infarction, n (%) | 1105 (1.13) | 196 (0.80) | 245 (1.00) | 312 (1.28) | 352 (1.44) | < 0.001 |
| Diabetes Mellitus, n (%) | 2860 (2.93) | 175 (0.72) | 311 (1.27) | 625 (2.56) | 1749 (7.17) | < 0.001 |
| Hypertension, n (%) | 11,450 (11.73) | 1720 (7.05) | 2379 (9.74) | 3255 (13.33) | 4096 (16.78) | < 0.001 |
| Hypercholesterolemia, n (%) | 5429 (5.56) | 691 (2.83) | 996 (4.08) | 1519 (6.22) | 2223 (9.11) | < 0.001 |
| Fasting plasma glucose, mmol/L | 5.11 (4.66–5.71) | 4.78 (4.38–5.20) | 5.01 (4.62–5.46) | 5.24 (4.80–5.81) | 5.66 (5.02–6.90) | < 0.001 |
| Triglycerides, mmol/L | 1.27 (0.89–1.93) | 0.70 (0.58–0.82) | 1.10 (0.98–1.22) | 1.56 (1.36–1.79) | 2.77 (2.18–3.90) | < 0.001 |
| HDL-C, mmol/L | 1.51 (1.28–1.77) | 1.54 (1.30–1.80) | 1.53 (1.31–1.77) | 1.49 (1.27–1.74) | 1.47 (1.25–1.75) | < 0.001 |
| LDL-C, mmol/L | 2.33 (1.82–2.83) | 2.13 (1.60–2.72) | 2.38 (1.92–2.82) | 2.41 (1.97–2.90) | 2.38 (1.82–2.88) | < 0.001 |
| Hs-CRP, mg/L | 0.80 (0.30–2.19) | 0.60 (0.21–1.90) | 0.72 (0.29–2.00) | 0.88 (0.33–2.20) | 1.03 (0.40–2.63) | < 0.001 |
| TyG index | 8.58 (8.18–9.05) | 7.91 (7.70–8.06) | 8.39 (8.29–8.48) | 8.79 (8.68–8.91) | 9.46 (9.23–9.82) | < 0.001 |
| Antidiabetic drugs, n (%) | 2185 (2.24) | 131 (0.54) | 224 (0.92) | 478 (1.96) | 1352 (5.54) | < 0.001 |
| Lipid-lowering drugs, n (%) | 796 (0.82) | 93 (0.38) | 158 (0.65) | 187 (0.77) | 358 (1.47) | < 0.001 |
| Antihypertensive drugs, n (%) | 9895 (10.13) | 1484 (6.08) | 2036 (8.34) | 2840 (11.63) | 3535 (14.48) | < 0.001 |
Data are given as median (interquartile range) unless otherwise indicated
HDL-C high-density lipoprotein cholesterol, LDL-C low-density lipoprotein cholesterol, Hs-CRP high-sensitive C-reactive protein, TyG index triglyceride-glucose