. 2021 Feb 19;21:90. doi: 10.1186/s12887-021-02523-4

Table 4.

Diagnostic value of combining different methods with a real-time polymerase chain reaction as the standard

	RT-PCR		Kappa	Sensitivity	Specificity	Accuracy	Youden Index
	Positive	Negative	Kappa	Sensitivity	Specificity	Accuracy	Youden Index
MP-RNA (SAT) + MP-IgM (PA)
Positive	256	112	0.602	84.2%	78.7%	80.7%	62.9%
Negative	48	414	0.602	84.2%	78.7%	80.7%	62.9%
MP-RNA (SAT) + MP-IgM (GICT)
Positive	223	76	0.591	73.4%	85.6%	81.1%	59.0%
Negative	81	450	0.591	73.4%	85.6%	81.1%	59.0%
MP-IgM (GICT) + MP-IgM (PA)
Positive	237	123	0.525	78.0%	76.6%	77.2%	54.6%
Negative	67	403	0.525	78.0%	76.6%	77.2%	54.6%
7 RNAs + MP-IgM (PA)
Positive	250	154	0.419	82.2%	70.7%	74.9%	52.9%
Negative	54	372	0.419	82.2%	70.7%	74.9%	52.9%
7 RNAs + MP-IgM (GICT)
Positive	198	120	0.419	65.1%	77.2%	72.8%	42.3%
Negative	106	406	0.419	65.1%	77.2%	72.8%	42.3%

SAT simultaneous amplification and testing

PA particle agglutination

GICT immune colloidal gold technique