Table 4.

Correlation between T lymphocyte (CD3+) infiltration and Treg (FOXP3+) infiltration in primary tumors, lymph node metastases, and distant metastases

		CD3 Lnm	CD3 Dm	FOXP3 Prim	FOXP3 Lnm	FOXP3 Dm
CD3 Prim	R	0,22	0,12	0,54	0,23	-0,24
	p	0,068	0,57	0,000	0,063	0,24
	N	69	26	172	68	26
CD3 Lnm	R		-0,39	0,26	0,55	0,23
	p		0,17	0,031	0,000	0,42
	N		14	70	78	14
CD3 Dm	R			-0,074	-0,47	0,61
	p			0,72	0,088	0,000
	N			26	14	34
FOXP3 Prim	R				0,19	-0,18
	p				0,12	0,37
	N				69	26
FOXP3 Lnm	R					-0,35
	p					0,22
	N					14

Abbreviations: R correlation coefficient, N number of patients included in analysis, Prim primary tumor, Lnm lymph node metastasis, Dm distant metastasis. Spearman correlati on, two-tailed P value. Bold indicates P value < 0.05