FIGURE 2.
Narrowing down the candidate factors. A–C, Relative expression levels of five mesenchymal (MES) and five adrenergic (ADRN) transcription factor (TF) genes normalized to ACTB in SH‐SY5Y neuroblastoma cells treated with different conditions for 48 h. A, Each of the 10 MES factors were individually removed. B, Three (interferon‐γ [IFN‐γ], tumor necrosis factor‐α [TNF‐α], and epidermal growth factor [EGF]) of the 10 MES factors were individually removed. C, Single or combinations of three factors (IFN‐γ, TNF‐α, and EGF) were added. ACTB, β‐actin; DHT, dihydrotestosterone; LTD4, leukotriene D4; TGF‐β1, transforming growth factor‐β1; VEGFA, vascular endothelial growth factor A