FIGURE 4.

Overexpression of miR‐182 in Jurkat cells and its effects on the expression of different targets and various cytokine secretion. A, Overexpression of miR‐182‐5p and ‐3p in Jurkat cells. B, Effects of miR‐182 on CD3d, FOXO1, ITK, NFATc3, NFATc4, IL‐2RA, and FOXP3 in Jurkat cells. C, Effects of miR‐182 on TNF‐α, IL‐6, TGF‐β, and IL‐2 expression. D, Effects of miR‐182 on TNF‐α, IL‐1β, IL‐6, IL‐10, IL‐17, TGF‐β, and IL‐2. Data represent mean ± SD (error bars) of three independent experiments in triplicate assays (***P < .001, **P < .01 and *P < .05)