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. 2020 Dec 22;112(2):589–603. doi: 10.1111/cas.14764

TABLE 2.

Summary of the microRNAs with at least one predicted target, which play a critical role in T cell activation and differentiation signal IL‐2/IL‐2RA

Targets
Isoform‐5p Isoform‐3p
hsa‐miR‐183 FOXO1 CD3d, NFATc4, NFAT5
hsa‐miR‐425 NFATc3 NFATc2
hsa‐miR‐93 NFAT5 NFATc1, NFATc3, NFATc4, NFAT5, CD3d, IL2RA
hsa‐miR‐410 ITK NFAT5
hsa‐miR‐182 FOXO1 NFATc3, NFATc4, CD3d, ITK, IL‐2RA
hsa‐miR‐486 FOXO1, NFAT5 NFATc2, NFATc4
hsa‐miR‐449b NFATc4, NFAT5
hsa‐miR‐200b NFATc3, NFAT5, ITK
hsa‐miR‐365a/b FOXO1, CD3d CD3d, FOXO1, IL‐2RA
hsa‐miR‐204 NFATc3, NFAT5 CD3d, NFATc3, NFATc4, NFAT5, IL2‐RA
hsa‐miR‐200c CD3d, ITK, NFATc2
hsa‐miR‐103a NFATc2, NFATc3, NFATc4, NFAT5, FOXO1, ITK, CD3d, IL‐2RA NFATc2, NFAT5
hsa‐miR‐125b FOXO1, NFAT5
hsa‐miR‐100 NFATc2, NFAT5
hsa‐miR‐490 CD3d, NFAT5, IL‐2RA FOXO1, NFAT5
hsa‐let‐7c FOXO1, ITK, NFATc1, NFATc2, NFATc3, NFAT5
hsa‐miR‐99b ITK, NFAT5
hsa‐miR‐383 NFAT5 NFATc3, NFAT5, CD3d
hsa‐miR‐21 NFAT5 CD3d, ITK, NFATc2, NFATc3, NFAT5
hsa‐miR‐127 NFATc2, ITK
hsa‐miR‐503 NFATc3, NFAT5
hsa‐miR‐195 FOXO1, NFATc2, NFATc3 FOXO1, CD3d, NFATc2
hsa‐miR‐511 FOXO1, NFATc3, NFATc4, NFAT5, IL‐2RA NFATc2, NFAT5
hsa‐miR‐134 FOXO1, CD3d, NFATc2, NFATc3
hsa‐miR‐342 NFATc1, NFATc3
hsa‐miR‐181d NFATc2, NFAT5