Table 1.
Clinical association between ENDOU expression and clinicopathological variables in HNSCC patients.
| Characteristics | n | No. of Patients (%) | ENDOU | ||
|---|---|---|---|---|---|
| Low | High | p | |||
| Status | 500 | 0.03 | |||
| Alive | 282(56.4) | 129 | 163 | ||
| Death | 218(43.6) | 121 | 97 | ||
| Gender | 500 | 0.011 | |||
| Female | 133(26.6) | 54 | 79 | ||
| Male | 367(73.4) | 196 | 171 | ||
| Age | 499 | 0.616 | |||
| <60 | 220(44.1) | 107 | 113 | ||
| ≥60 | 279(55.9) | 142 | 137 | ||
| Alcohol_history | 489 | 0.017 | |||
| No | 157(32.1) | 66 | 91 | ||
| Yes | 332(67.9) | 178 | 154 | ||
| Clinical_N | 478 | 0.001 | |||
| N0 | 239(50) | 101 | 138 | ||
| N1-3 | 239(50) | 139 | 100 | ||
| Clinical_T | 485 | 0.731 | |||
| T1-2 | 176(36.3) | 86 | 90 | ||
| T3-4 | 309(63.7) | 156 | 153 | ||
| Clinical_stage | 486 | 0.096 | |||
| I-II | 114(23.5) | 49 | 65 | ||
| III-IV | 372(76.5) | 193 | 179 | ||
| Lymph_node_count | 407 | 0.52 | |||
| Low | 203(49.9) | 102 | 101 | ||
| High | 204(50.1) | 96 | 108 | ||
| Lymphovascular_invasion_present | 339 | 0.001 | |||
| No | 219(64.6) | 95 | 124 | ||
| Yes | 120(35.4) | 74 | 46 | ||
| Neoplasm_histologic_grade | 481 | 0 | |||
| G1-2 | 360(74.8) | 151 | 209 | ||
| G3-4 | 121(25.2) | 88 | 33 | ||
| Recurrence | 442 | 0.39 | |||
| No | 317(71.7) | 153 | 164 | ||
| Yes | 125(28.3) | 66 | 59 | ||
| Pathologic_N | 407 | 0 | |||
| N0 | 171(42.0) | 63 | 108 | ||
| N1-3 | 236(58.0) | 132 | 104 | ||
| Pathologic_T | 444 | 0.799 | |||
| T1-2 | 177(39.9) | 84 | 93 | ||
| T3-4 | 267(60.1) | 130 | 137 | ||
| Pathologic_stage | 435 | 0.133 | |||
| I-II | 98(22.5) | 41 | 57 | ||
| III-IV | 337(77.5) | 170 | 167 | ||
| Perineural_invasion | 351 | 0.311 | |||
| No | 186(53.0) | 88 | 98 | ||
| Yes | 165(47.0) | 87 | 78 | ||
| Smoker | 490 | 0.914 | |||
| No | 111(22.7) | 56 | 55 | ||
| Yes | 379(77.3) | 189 | 190 | ||