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. 2021 Feb 16;9:e10668. doi: 10.7717/peerj.10668

Figure 5. Functional analysis of differentially expressed mRNA genes.

Figure 5

(A and B) The top 10 GO analysis terms for upregulated (A) and downregulated (B) DEGs in LN mice. (C) The number of upregulated and downregulated immune and inflammatory genes in LN mice. (D) Hierarchical clustering and heatmap of six samples based on all the differentially expressed immune and inflammatory genes. (E and F) The KEGG pathway for upregulated (E) and downregulated (F) DEGs in LN mice. (G) Hierarchical clustering and heatmap of six samples based on all differentially expressed SLE-associated genes. (H) Overlap of the differentially expressed inflammatory genes and SLE-associated genes.