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. 2021 Feb 16;9:e10668. doi: 10.7717/peerj.10668

Figure 6. Functional analysis of differentially expressed lncRNA genes.

Figure 6

(A) Number of DElncRNAs and their cis-target mRNA genes. (B–E) RT-qPCR validation of the expression levels of four DElncRNAs and their cis-target mRNAs. (F) The top 10 GO analysis terms for DElncRNA cis-target mRNA genes. (G) The KEGG pathway for DElncRNA cis-target mRNA genes. (H) Coexpression network between DElncRNAs and six cis-target SLE and immune genes. (I–L) RT-qPCR validation of the expression levels of the DElncRNA Gm20513 and its cis-target SLE gene (H2-Aa). RNA-seq (FPKM) and RT-qPCR are presented. Data are presented as the mean ±  standard deviation (SD). Student’s t-test was performed to compare LN and control mice with the significance set at a P value of less than 0.05. * P < 0.05, ** P < 0.01, *** P < 0.01.