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. 2020 Oct 16;48(2):190–198. doi: 10.1111/1346-8138.15650

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© 2020 The Authors. The Journal of Dermatology published by John Wiley & Sons Australia, Ltd on behalf of Japanese Dermatological Association

This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.

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(a,c,e) Histopathological findings (hematoxylin–eosin, original magnifications: [a] ×100, [c] ×200, [e] ×100) and (b,d,f) Fontana‐Masson staining of scabies burrows showing the gray‐edged line sign ([b] ×400, [d] ×200, [f] ×200). (a–d) A scabies burrow obtained from the right lateral chest in case 15. A mite (asterisk), eggs (black arrows) and feces (black arrowheads) are apparent. Some melanin‐rich keratinocytes are seen in contact with the wall of the scabies burrow (white arrowheads). (e,f) Scabies burrow obtained from the back in case 26.