Figure 12.

Micelles formed by the block copolymer from dPGS and poly(ϵ‐caprolactone) for active targeting of inflammation‐related tumor tissues. ^[38] The micelles are assembled from a block copolymer consisting of a highly charged dPGS block and a hydrophobic poly(caprolactam) block. Both parts are interlinked by a sulfur bridge, which will be cleaved in the reductive environment of the cell. The drug doxorubicin (DOX) can be encapsulated in the hydrophobic core and, thus, brought to the infected tissue by intravenous injection. After uptake in the cells, the S‐S bridges are cleaved and the drug is released.