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CD28 copy number variation (CNV) in adult T‐cell leukaemia/lymphoma (ATL) by fluorescence in situ hybridization (FISH). FISH analyses on FFPE sections from eight individual ATL patients. CD28 signals on chromosome 2q33 are green, and centromeric signals of chromosome 2 are red. CD28 signal number: centromeric signal number ratios were 7:2 (A), 6:3 (B), 5:2 (C), 4:2 (D), 3:2 (E) and 2:2 (F). [Colour figure can be viewed at wileyonlinelibrary.com]
