Table 1.
Preintervention Baseline Characteristics of Patients
| Characteristic | Patients surviving 1‐year follow up (n = 278) | Patients who died before 1‐year follow up (n = 52) |
|---|---|---|
| General characteristics | ||
| Age, years, median (IQR) | 83.4 (5.5) | 84.2 (6.4) |
| Female gender, n (%) | 157 (56.5) | 29 (55.8) |
| Body mass index, kg/m2, median (IQR) | 25.3 (5.4) | 24.0 (5.1) |
| Number of comorbidities a , median (IQR) | 3.0 (2.0) | 4.0 (2.0) b |
| Cardiac parameters | ||
| Dyspnea NYHA class III or IV, n (%) | 182 (65.5) | 37 (71.2) |
| Angina CCS score III or IV, n (%) | 38 (13.7) | 5 (9.6) |
| Left ventricular ejection fraction, %, median (IQR) | 60.0 (20.0) | 50.0 (25.0) b |
| Mean gradient aortic valve, mmHg, median (IQR) | 42.0 (21.0) | 38.0 (24.5) |
| Aortic valve area, cm2, median (IQR) | 0.6 (0.3) | 0.6 (0.3) |
| Comprehensive geriatric assessment parameters | ||
| Cognitive impairment (MMSE <27 points), n (%) | 85 (30.6) | 25 (48.1) b |
| Mobility impairment (TUG ≥20 seconds), n (%) | 81 (29.1) | 32 (61.5) b |
| At risk of malnutrition (MNA <12 points), n (%) | 120 (43.2) | 34 (65.4) b |
| Basic ADL ≥1 limitation, n (%) | 62 (22.3) | 20 (38.5)b |
| Instrumental ADL ≥1 limitation, n (%) | 181 (65.1) | 35 (67.1) |
| Preclinical mobility disability c , n (%) | 170 (61.1) | 35 (67.1) |
| Risk scores | ||
| Frailty status: nonfrail (frailty index <3), n (%) | 146 (52.5) | 15 (28.8) b |
| Frailty status: frail (frailty index 3 or 4), n (%) | 98 (35.3) | 18 (34.6) |
| Frailty status: very frail (frailty index ≥5), n (%) | 34 (12.2) | 19 (36.5) b |
| Logistic EuroSCORE, median (IQR) | 18.1 (15.7) | 28.1 (21.4) b |
| STS score, median (IQR) | 5.6 (3.8) | 7.3 (5.7) b |
Abbreviations: ADL, activities of daily living; CCS, Canadian Cardiovascular Society; IQR, interquartile range; MMSE, Mini Mental State Exam; MNA, Mini Nutritional Assessment; NYHA, New York Heart Association; STS, Society of Thoracic Surgeons; TAVI, transcatheter aortic valve implantation; TUG, timed get up and go test.
a
Extracted from clinical records, based on a list of 10 chronic conditions. 10
b
Significant group difference (P < .05) between surviving patients and patients who died based on chi‐squared test or Kruskal‐Wallis test.
c
Self‐reported decreased frequency of walking 200 m or of climbing stairs during the 6 months before baseline. 18