Table 1.
Ventilatory, metabolic, and circulatory data from the first prone positioning session
| Parameter. median (IQR) | 1 h before prone | 1 h after prone | 1 h before supine | 1 h after supine | P‐value |
|---|---|---|---|---|---|
| PaO2:FiO2 (mm Hg) | 104 (86‐122) | 151 (105‐178) | 161 (127‐207) | 135 (106‐177) | <.001 |
| FiO2 | 0.7 (0.6‐0.8) | 0.6 (0.5‐0.7) | 0.5 (0.35‐0.6) | 0.58 (0.45‐0.7) | <.001 |
| Pao2 (mm Hg) | 72 (65‐83) | 78 (73‐95) | 74 (68‐81) | 71 (65‐77) | .49 |
| Paco2 (mm Hg) | 46 (41‐52) | 48 (42‐54) | 46 (41‐51) | 46 (41‐54) | .50 |
| Tidal volume (ml) | 438 (376‐510) | 445 (385‐513) | 445 (400‐536) | 450 (396‐490) | .46 |
| Tidal volume (ml per kg of PBW) | 6 (6‐8) | 6 (6‐8) | 6 (6‐9) | 7 (6‐7) | .42 |
| Respiratory frequency (breaths per min) | 20 (17‐22) | 20 (17‐25) | 22 (17‐26) | 22 (20‐25) | .07 |
| PEEP (cm H2O) | 11 (9‐12) | 10 (10‐12) | 10 (8‐11) | 10 (9‐11) | .12 |
| Plateau (cm H2O) | 25 (21‐30) | 25 (21‐28) | 25 (21‐29) | 24 (22‐29) | .75 |
| Arterial pH | 7.36 (7.33‐7.39) | 7.35 (7.30‐7.38) | 7.37 (7.33‐7.41) | 7.37 (7.33‐7.40) | .12 |
| Base Excess | 1 (−2‐2.3) | 0 (−2‐1.8) | 1 (−1‐3) | 1 (−1‐3) | .10 |
| MAP (mm Hg) | 75 (68‐82) | 79 (70‐83) | 77 (72‐82) | 75 (70‐80) | .65 |
| Norepinephrine (µg/kg/min) | 0.06 (0.01‐0.1) | 0.06 (0.02‐0.15) | 0.05 (0.02‐0.15) | 0.07 (0.03‐0.18) | .56 |
| Time in prone position (h) | 14.5 (13.0‐18.0) | ||||