Table 4.
Discontinuation of medication related to numbers of pills and cardiovascular antecedents.
| Univariate Logistic | Multivariate Logistic | |||||
|---|---|---|---|---|---|---|
| OR crude | 95%CI | P value | Adjusted OR | 95%CI | P value | |
| Male sex | 0.92 | 0.78–1.08 | 0.312 | 1.01 | 0.86–1.20 | 0.819 |
| Pills per day | ||||||
| - Less than 4 | Baseline | N/A | N/A | Baseline | N/A | N/A |
| - 5–8 | 0.85 | 0.70–1.02 | 0.096 | 0.80 | 0.65–0.99 | 0.047 |
| - 9–12 | 1.19 | 0.83–1.70 | 0.335 | 1.07 | 0.73–1.59 | 0.698 |
| - More than 12 | 1.28 | 0.51–3.18 | 0.590 | 1.09 | 0.42–2.80 | 0.857 |
| Cardiovascular History | ||||||
| Stroke | 0.72 | 0.45–1.14 | 0.163 | 0.70 | 0.44–1.12 | 0.147 |
| Peripheral vascular disease | 1.54 | 1.08–2.19 | 0.015 | 1.55 | 1.08–2.24 | 0.018 |
| Coronary disease | 1.16 | 0.94–1.41 | 0.148 | 1.29 | 1.04–1.60 | 0.018 |
| Diabetes | 1.01 | 0.83–1.23 | 0.883 | 1.08 | 0.88–1.33 | 0.411 |
| Hypertension | 0.74 | 0.62–0.88 | 0.001 | 0.86 | 0.71–1.03 | 0.119 |
| Dyslipidemia | 0.81 | 0.68–0.96 | 0.016 | 0.85 | 0.71–1.02 | 0.084 |
| Heart failure | 1.44 | 1.13–1.84 | 0.003 | 1.36 | 1.05–1.75 | 0.017 |
| Cardiomyopathy | 1.49 | 1.04–2.15 | 0.029 | 1.30 | 0.89–1.91 | 0.172 |
| Valvular heart disease | 1.77 | 1.37–2.29 | <0.001 | 1.66 | 1.27–2.17 | <0.001 |
| Arrhythmias | 0.97 | 0.78–1.21 | 0.833 | 0.90 | 0.72–1.12 | 0.357 |
| Cardiac devices | 1.04 | 0.69–1.57 | 0.834 | 0.95 | 0.62–1.45 | 0.816 |
| Depression | 2.02 | 1.72–2.38 | 0.000 | 2.01 | 1.71–2.37 | <0.001 |