TABLE 2.
Laboratory results, radiographic findings, clinical outcome among different Groups.
|
Characteristic Median (range) or No., % |
Normal range | Total | Group 1 | Group 2 | p value |
|---|---|---|---|---|---|
| N = 123 | N = 49 | N = 74 | |||
| WBC Count, ×109/L | 3.5‐9.5 | 5.12(2.02‐14.27) | 4.84(2.02‐12.4) | 5.56 (2.8‐14.27) | 0.03 |
| Neutrophil count (×109/L) | 1.8‐6.3 | 3.61 (1‐12.32) | 3.33 (1‐9.97) | 3.93 (1.48‐12.32) | 0.043 |
| Lymphocyte count (×109/L) | 1.1‐3.2 | 0.91 (0.3‐1.83) | 0.81 (0.3‐1.74) | 0.94 (0.32‐1.83) | 0.159 |
| Platelet Count, ×109/L | 125‐350 | 164 (39‐867) | 165 (39‐416) | 164 (61‐867) | 0.222 |
| Hemoglobin, g/L | 115‐150 | 95 (48‐163) | 90 (48‐163) | 99 (51‐134) | 0.161 |
| Albumin, g/L | 40‐55 | 37.3 (26.9‐51.8) | 34.4 (26.9‐46.7) | 38.7 (29.7‐51.8) | 0.001 |
| ALT, U/L | 9‐50 | 11 (1‐80) | 11 (3‐26) | 12 (1‐80) | 0.562 |
| AST, U/L | 13‐40 | 14 (4‐56) | 15 (5‐56) | 12 (4‐44) | 0.02 |
| LDH, U/L | 120‐250 | 199 (95‐382) | 212 (112‐382) | 192 (95‐333) | 0.105 |
| CK, U/L | 50‐310 | 70 (15‐801) | 71 (15‐253) | 68 (24‐801) | 0.576 |
| CK‐MB, U/L | 0‐24 | 8 (1‐40) | 8 (1‐40) | 8 (2‐21) | 0.818 |
| Blood glucose, mmol/L | 3.9‐6.1 | 6.16 (2.29‐29.86) | 5.24 (2.29‐17.7) | 7.36 (3.8‐29.86) | 0.001 |
| BUN, mmol/L | 3.1‐8.8 | 26.2 (6.04‐62.14) | 24.63 (6.04‐62.14) | 26.84 (6.5‐48.11) | 0.211 |
| Creatinine, μmol/L | 41‐81 | 942.8 (286.9‐2513) | 890.3 (286.9‐2513) | 956 (421‐1899) | 0.255 |
| PT, s | 9‐13 | 11.9 (9.3‐16.6) | 11.7 (9.3‐15) | 12.2 (9.9‐16.6) | 0.137 |
| APTT, s | 20‐40 | 30.7 (19.2‐70.2) | 30.9 (19.2‐52.9) | 30.1 (20.1‐70.2) | 0.757 |
| D‐DIMER, ng/ml | <0.5 | 0.85 (0.11‐14.17) | 1.4 (0.22‐10.84) | 0.65 (0.11‐14.17) | 0.001 |
| PCT, ng/ml | 0‐0.05 | 0.56 (0.04‐3.86) | 0.57 (0.04‐3.86) | 0.55 (0.19‐3.18) | 0.347 |
| hs‐CRP, mg/L | 0‐10 | 11.2 (0.61‐142.6) | 21.75 (0.61‐142.6) | 4.6 (1.2‐119) | 0.007 |
| Calcium, mmol/L | 2.11‐2.52 | 2.22 (1.42‐2.63) | 2.13 (1.42‐2.56) | 2.27 (1.82‐2.63) | 0.007 |
| Phosphorus, mmol/L | 0.85‐1.51 | 1.87 (0.91‐3.97) | 1.81 (0.91‐3.97) | 1.94 (1.04‐2.9) | 0.41 |
| Ferritin, ng/ml | 13‐400 | 276 (22.8‐1651) | 384.5 (56.3‐1651) | 243.2 (22.8‐1651) | 0.017 |
| PTH, ng/L | 15‐65 | 402.6 (10.4‐2685) | 460.2 (69.8‐1162.8) | 377.8 (10.4‐2685) | 0.92 |
| Lymphocyte subsets | |||||
| T cells, % | 62.64‐76.76 | 69.9 (40‐88) | 70.5 (48‐88) | 69.7 (40‐84) | 0.589 |
| CD8+ T cells, % | 19.17‐33.63 | 24 (11‐45) | 26 (11‐45) | 23 (11‐45) | 0.307 |
| CD4+ T cells, % | 30‐46 | 41 (18‐70) | 40 (18‐70) | 42 (20‐57) | 0.466 |
| Natural killer cells, % | 9.5‐23.5 | 18 (2‐46) | 17.5 (5‐42) | 18 (2‐46) | 0.931 |
| B cells, % | 8.48‐14.5 | 7 (1‐22) | 6 (2‐17) | 8 (1‐22) | 0.214 |
| CD4/CD8 ratio | 0.947‐2.125 | 1.63 (0.4‐4.67) | 1.56 (0.4‐4.67) | 1.69 (0.51‐4.0) | 0.378 |
| Chest CT scan findings‐No., % | |||||
| Normal | 12 | 2 (4.2%) | 10 (14.1%) | <0.001 | |
| Unilateral pneumonia | 16 | 0 (0.0%) | 16 (22.5%) | ||
| Bilateral pneumonia | 21 | 7 (14.6%) | 14 (19.7%) | ||
| Ground‐glass opacity | 39 | 22 (45.8%) | 17 (23.9%) | ||
| Unilateral or bilateral patchy shadowing | 31 | 17 (35.4%) | 14 (19.7%) | ||
| Clinical outcome in Group 1 | |||||
| Died | 2 (4.1%) | — | |||
| Discharged | 43 (87.7%) | ||||
| Remained in hospital | 4 (8.2%) | ||||
Abbreviations: APTT, activated partial thromboplastin time; BUN, blood urea nitrogen; CK, creatine kinase; CK‐MB, creatinine kinase–myocardial band; hs‐CRP, hypersensitive c‐reactive protein; LDH, lactate dehydrogenase; PCT, procalcitonin; PT, prothrombin time; PTH, parathyroid hormone; WBC, white blood cell.