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. 2020 Nov 13;73(2):606–624. doi: 10.1002/hep.31290

FIG. 4.

FIG. 4

LPI inhibits lipogenesis and promotes β‐oxidation in hepatocytes through GPR55. De novo (A) triglyceride, diacylglyceride, and fatty acid lipogenesis and (B) palmitate oxidation in HepG2 human cells treated with vehicle or LPI and down‐regulating GPR55 (n = 4‐5). Data are presented as mean ± SEM. Statistical differences are denoted by *P < 0.05 and **P < 0.01. Abbreviations: GPR55, G protein–coupled receptor 55; LPI, l‐α‐lysophosphatidylinositol; siCTRL, small interfering RNA control; siGPR55, small interfering RNA GPR55.