Table 4.
Change in disease‐related assessment in patients with psoriatic arthritis
| Baseline | Week 4 | Week 12 | Week 16 | Week 24 | |
|---|---|---|---|---|---|
| HAQ‐DI (mean ± SD) | 0.72 ± 0.732 (n = 12) | 0.37 ± 0.503 (n = 10) | 0.33 ± 0.432 (n = 10) | 0.25 ± 0.294 (n = 11) | 0.47 ± 0.585 (n = 10) |
| DAS28‐CRP | 3.43 ± 1.559 (n = 19) | 2.20 ± 0.811 (n = 10) | 2.20 ± 0.878 (n = 16) | 1.94 ± 0.568 (n = 5) | 2.20 ± 0.725 (n = 12) |
| VAS (patient) | 59.5 ± 29.20 (n = 22) | 28.7 ± 25.60 (n = 15) | 23.1 ± 24.47 (n = 21) | 18.1 ± 20.62 (n = 16) | 23.2 ± 28.32 (n = 17) |
| VAS (physician) | 56.3 ± 27.48 (n = 21) | 33.3 ± 25.05 (n = 13) | 21.6 ± 21.35 (n = 19) | 18.1 ± 20.80 (n = 15) | 16.6 ± 20.52 (n = 17) |
| BASDAI | 5.04 ± 2.852 (n = 17) | 3.53 ± 2.664 (n = 13) | 2.85 ± 2.368 (n = 17) | 1.78 ± 1.643 (n = 16) | 2.25 ± 2.210 (n = 15) |
| Dactylitis † | 2.1 ± 2.91 (n = 30) | 1.4 ± 2.09 (n = 21) | 1.1 ± 2.07 (n = 28) | 0.7 ± 1.56 (n = 23) | 0.3 ± 1.27 (n = 23) |
| Tender DIP joint count † | 2.8 ± 3.29 (n = 30) | 0.9 ± 1.87 (n = 21) | 0.8 ± 1.40 (n = 27) | 0.3 ± 0.83 (n = 23) | 0.4 ± 1.14 (n = 22) |
| Swollen DIP joint count † | 3.3 ± 3.80 (n = 30) | 1.0 ± 1.86 (n = 21) | 1.2 ± 1.91 (n = 27) | 1.0 ± 1.81 (n = 23) | 0.9 ± 2.02 (n = 22) |
| Tenderness in entheses (LEI) (patients with ≥1 symptom), % (n/M) | 19.12 (13/68) | 6.25 (3/48) | 12.07 (7/58) | 4.17 (2/48) | 8.77 (5/57) |
| Global impression of change of joint symptoms (Response rate ‡ ), % (n/M) | NA | 86.49 (32/37) | 80.77 (42/52) | 90.70 (39/43) | 87.50 (42/48) |
†
Finger and toes.
‡
Response rate = complete response + partial response. BASDAI, Bath Ankylosing Spondylitis Disease Activity Index; DIP, distal interphalangeal; HAQ‐DI, Japanese Health Assessment Questionnaire Disability Index; LEI, Leeds Enthesitis Index; M, number of patients assessed; n, number of patients; NA, not applicable; SD, standard deviation; VAS, visual analog scale.