Figure 8.

Overexpression of SMARCA5 inhibited cervical cancer metastasis in vivo. HeLa cells transfected with the pLO-ciR empty vector or pLO-ciR-SMARCA5 were inoculated into nude mice to establish subcutaneous xenograft tumor models. (A) The tumor volume was monitored every week. n = 3. **P < 0.01, one-way ANOVA. After the mice were sacrificed, (B) the tumor mass was measured, (C-E) the expression of SMARCA5 was detected by RT-qPCR, and the expressions of SND1, YWHAB, and anti-apoptotic proteins were detected by western blotting, the quantification was performed using Image J software. n = 3. *P < 0.05, **P < 0.01, one-way ANOVA.

ANOVA: analysis of variance.