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. 2021 Feb 16;12:2041731420974147. doi: 10.1177/2041731420974147

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© The Author(s) 2021

This article is distributed under the terms of the Creative Commons Attribution 4.0 License (https://creativecommons.org/licenses/by/4.0/) which permits any use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access page (https://us.sagepub.com/en-us/nam/open-access-at-sage).

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Figure 4. — (a) H₂O₂ concentration of the acellular growth media (GM) in function of the electrical stimulation (ES) time. Error bars represent SD (n = 6 replicates), and dash line represents linear trend line. (b) The reduction in H₂O₂ concentration of the acellular GM after 1 h of ES by sodium pyruvate ranging from 1 to 20 mM relative to 0 mM. Error bars represent SD (n = 3 replicates). * represents p < 0.05 (one-way ANOVA with Tukey’s pairwise comparison) when compared with 1 mM. (c) H₂O₂ concentration of the acellular GM after 1 h of ES without and with 5 mM sodium pyruvate. Error bars represent SD (n = 3 experiments). *represents p < 0.05 (unpaired two-tailed Student’s t-test) when compared with GM without sodium pyruvate. (d) Measured dissolved Pt content in the acellular GM after 1 h of ES using ICP-MS. Error bars represent SD (n = 3 experiments).