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. Author manuscript; available in PMC: 2022 Mar 1.
Published in final edited form as: J Stroke Cerebrovasc Dis. 2021 Jan 12;30(3):105595. doi: 10.1016/j.jstrokecerebrovasdis.2020.105595

Figure 1. Glibenclamide improves neuro score, stroke volumes and brain edema in cohort 1.

Figure 1.

(A) Immediately after reperfusion, there was no difference between the two groups (p=0.46). (B) At 48 hours, glibenclamide improved the neurological score (* p<0.05). Both indirect (C) and direct (D) stroke volume were significantly reduced by glibenclamide (** p<0.01). The swelling volume of ischemic core (E) and the ipsilateral, surrounding TTC positive brain tissue (F) were significantly reduced by glibenclamide (* p<0.05, ** p<0.01, respectively). (G) Concomitantly, estimated total brain water content was reduced by glibenclamide (* p<0.05).