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. 2020 Dec 18;32(1):9–31. doi: 10.1681/ASN.2020050697

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Figure 1. — Sphingolipid metabolites and enzymes are compartementalized within the cell. ABCC1, ATP-binding cassette transporter C1; aCDase, alkaline ceramidase; ACER, alkaline ceramidase; aSMase, acid sphingomyelinase; CERK, ceramide kinase; CERS, ceramide synthase; C1P, ceramide-1-phosphate; C1PP, ceramide-1-phosphate phosphatase; DES1, dihydroceramide desaturase 1; DHC, dihydroceramide; GlcCer, glucosylceramide; HD, hexadecenal; 3-KDS, 3-ketodihydrosphingosine; KDSR, 3-ketosphingosine; MA-nSMase, mitochondria-associated neutral sphingomyelinase; MFSD2B, Major Facilitator Superfamily Domain Containing 2B; nCDase, neutral ceramidase; nSMase2, neutral sphingomyelinase 2; PE, phosphoethanolamine; SGPL1, sphingosine-1-phosphate lyase 1; SM, sphingomyelin; SMS, sphingomyelin synthase; Sph, sphinganine; SPHK, sphingosine kinase; Spns2, Shingolipid Transporter 2; SPP, sphingosine-1-phosphate phosphatase; SPT, serine-palmitoyl-transferase; S1PR, sphingosine-1-phosphate receptor.