Figure 2.

Higher plasma biomarker concetrations (per increment in log2 biomarker values) of KIM-1, TNFR-1, TNFR-2, MCP-1, suPAR, and YKL-40 were associated with a greater risk of DKD progression, even after adjustment for age, sex, race/ethnicity, education, clinical center, systolic BP, diastolic BP, BMI, hsCRP, hemoglobin A1c, antihypertensive medication use, smoking status, baseline eGFR (ml/min per 1.73 m²), and UPCR. All HRs are adjusted for age, sex, race/ethnicity, education, clinical center, systolic BP, diastolic BP, BMI, hsCRP, hemoglobin A1c, antihypertensive medication use, smoking status, baseline eGFR (ml/min per 1.73 m²), and UPCR.