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. 2020 Dec 7;32(1):99–114. doi: 10.1681/ASN.2020050698

Figure 4.

Figure 4.

Functional and molecular characteristics of C3hu/hu mice. (A and B) Graphs depicting the results of BUN and sCysC, respectively, in WT (n=6) and C3hu/hu mice (n=9). (C) Graph depicting the results of urinary albumin per day and urinary albumin normalized to creatinine, respectively, in WT (n=6) and C3hu/hu mice (n=9). (D) Gene-set enrichment analysis31 of genes differentially expressed between C3hu/hu mice and their WT controls. Graph shows subset of the MsigDB hallmark gene sets with adjusted P value for enrichment <10−3. uAlb, urinary albumin; uCreat, urinary creatinine. *P<0.05, **P<0.01, ****P<0.0001.