Table 4. Comparison of the genetic inheritance models for GSTP1 rs1695 polymorphism and allelic association in ALS patients.
| Models | Genotype | Control (101) | Case (101) | OR (CI 95%) | pa | AIC | BIC |
|---|---|---|---|---|---|---|---|
| Codominant | A/A | 42 (41.6%) | 53 (52.5%) | 1.00 | 0.170 | 282.4 | 292.4 |
| A/G | 47 (46.5%) | 42 (41.6%) | 0.71 (0.40–1.27) | ||||
| G/G | 12 (11.9%) | 6 (5.9%) | 0.40 (0.14–1.14) | ||||
| Dominant | A/A | 42 (41.6%) | 53 (52.5%) | 1.00 | 0.120 | 281.6 | 288.2 |
| A/G-G/G | 59 (58.4%) | 48 (47.5%) | 0.64 (0.37–1.12) | ||||
| Recessive | A/A-A/G | 89 (88.1%) | 95 (94.1%) | 1.00 | 0.140 | 281.8 | 288.4 |
| G/G | 12 (11.9%) | 6 (5.9%) | 0.47 (0.17–1.30) | ||||
| Overdominant | A/A-G/G | 54 (53.5%) | 59 (58.4%) | 1.00 | 0.480 | 283.5 | 290.1 |
| A/G | 47 (46.5%) | 42 (41.6%) | 0.82 (0.47–1.43) | ||||
| Logarithmic | 0.66 (0.43–1.03) | 0.062 | 280.6 | 287.2 | |||
| Allele | |||||||
| A | 131 (65%) | 148 (73%) | 0.085 | ||||
| G | 71 (35%) | 54 (27%) |
aThe comparison of the genetic inheritance models was obtained by logistic regression and the allelic association was evaluated by Fisher’s exact test. All study participants were matched by gender and age, and therefore this adjustment was not necessary for logistic regression. Abbreviations: OR = Odds Ratio; CI = Confidence Interval 95%; AIC = Akaike Information Criteria; BIC = Bayesian Information Criteria. Significance between groups: p<0.05.