Table 7. Association between GSTP1 rs1695 genotypes and the characteristics of the ALS patients.
| Variables | GSTP1 n (%) | pa | ||
|---|---|---|---|---|
| A/A | A/G | G/G | ||
| Gender | ||||
| Female | 24 (45.3) | 18 (42.9) | 3 (50.0) | 0.93 |
| Male | 29 (54.7) | 24 (57.1) | 3 (50.0) | |
| Physical Activity | ||||
| No | 24 (45.3) | 21 (50.0) | 2 (33.3) | 0.72 |
| Yes | 29 (54.7) | 21 (50.0) | 4 (66.7) | |
| Environmental exposure | ||||
| No | 32 (60.4) | 35 (83.3) | 5 (83.3) | 0.03* |
| Yes | 21 (39.6) | 7 (16.7) | 1 (16.7) | |
| Alcohol Intake | ||||
| No | 29 (54.7) | 22 (52.4) | 4 (66.7) | 0.80 |
| Yes | 24 (45.3) | 20 (47.6) | 2 (33.3) | |
| Smoking | ||||
| No | 34 (64.2) | 29 (69.0) | 2 (33.3) | 0.23 |
| Yes | 19 (35.8) | 13 (31.0) | 4 (66.7) | |
| Classification | ||||
| Sporadic ALS | 52 (98.1) | 37 (88.1) | 6 (100.0) | 0.10 |
| Familiar ALS | 1 (1.9) | 5 (11.9) | 0 (0.0) | |
| Neurological Disease in Family | ||||
| No | 30 (56.6) | 26 (61.9) | 4 (66.7) | 0.81 |
| Yes | 23 (43.4) | 16 (38.1) | 2 (33.3) | |
| Complications | ||||
| No | 38 (71.7) | 29 (69.0) | 4 (66.7) | 0.94 |
| Yes | 15 (28.3) | 13 (31.0) | 2 (33.3) | |
| Previous pathologies | ||||
| No | 28 (52.8) | 25 (59.5) | 1 (16.7) | 0.14 |
| Yes | 25 (47.2) | 17 (40.5) | 5 (83.3) | |
| Riluzole Use | ||||
| No | 11 (20.8) | 11 (26.2) | 3 (50.0) | 0.27 |
| Yes | 42 (79.2) | 31 (73.8) | 3 (50.0) | |
*Significant difference between groups (p<0.05). aPost Hoc chi-square test. All p-values were corrected by the Bonferroni adjustment for multiple comparisons tests. Abbreviation: n = Absolute Frequency. Significance between groups: p<0.05.