Table 1. Summary of patient characteristics and laboratory results.
| Cohort 1 (N = 126) | Cohort 2 (N = 39) *** | ||||
|---|---|---|---|---|---|
| Group 1 | Group 2 | Group 3 | Group 2 | Group 3 | |
| no elevation | ALT < 10x UNL | ALT > 10x UNL | ALT < 10x UNL | ALT > 10x UNL | |
| N (% of total cohort) | 80 (63.5) | 39 (31.0) | 7 (5.6) | 31 (79.5) | 8 (20.5) |
| Male | 34 (42.5) | 23 (59.0) | 6 (85.7) | 26 (83.9) | 7 (87.5) |
| ■ Age (Mean/SD) | 60/18 | 77/9 | 68/14 | 64/15 | 70/16 |
| Female | 46 (57.5) | 16 (41.0) | 1 (14.3) | 5 (16.1) | 1 (12.5) |
| ■ Age (Mean/SD) | 60/20 | 68/20 | 72 * | 70/16 | 80 * |
| Inpatient treatment | 42 (52.5) | 39 (100) | 7 (100) | 31 (100) | 8 (100) |
| ICU treatment | 1 (1.3) | 28 (71.8) | 7 (100) | 31 (100) | 8 (100) |
| Death | 1 (1.3) | 11 (28.2) | 5 (71.4) | 13 (41.9) | 8 (100) |
| Positive sonography | 3 (7.7) | 5 (71.4) | 12 (38.7) | 7 (87.5) | |
| Max. lab parameter (Mean/SD): | |||||
| AST | ** | 191/140 | 3302/2975 | 324/222 | 3754/2576 |
| ALT | ** | 131/73 | 1254/741 | 166/101 | 1263/740 |
| ALP | ** | 208/167 | 656/385 | 404/331 | 680/425 |
| GGT | ** | 329/394 | 1187/928 | 824/764 | 1213/906 |
| Total Bilirubin | ** | 3.0/4.9 | 7.5/7.9 | 8.2/11.0 | 12.4/13.1 |
ALT, alanine aminotransferase; AST, aspartate aminotransferase; GGT, gamma-glutamyl transferase; ALP, alkaline phosphatase; UNL, upper normal limit.
* One patient only.
** Parameters in normal range or not measured.
*** 14 patients are also part of cohort 1 (10 in group 2, 4 in group 3).