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. 2021 Feb 5;12:616686. doi: 10.3389/fgene.2021.616686

FIGURE 2.

FIGURE 2

FDP-TPR curves of DE methods on simulated Usoskin datasets and Tung datasets. (A) Line plot of the FDP-TPR curves for simulated Usoskin datasets generated by splatter for each of 12 DE methods. (B) Line plot of the FDP-TPR curves for simulated Tang datasets generated by splatter for each of 12 DE methods. Circles represent values at a 0.05 nominal FDR threshold and are filled in if the FDP (i.e., empirical FDR) is less than 0.05. DE, differential expression; TPR, true positive rate; FDP, false discovery proportion; FDR, false discovery rate.