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. 2021 Feb 19;16(2):e0246957. doi: 10.1371/journal.pone.0246957

Table 2. Relative abundance of genus level taxa (percent of total sequences) in the fecal microbiota of cats undergoing PCR testing for naturally occurring T. foetus infection.

Phylum Family Genus Median % abundance [range min to max] Kruskal-Wallis ANOVA p-value
PCR Positive (n = 17 cats) PCR Negative (n = 72 cats)
Actinobacteria     5.19 [0.78–21.59] 3.63 [0.04–39.61]  0.484 
Bifidobacteriaceae Bifidobacterium 0.03 [0.0–5.79] 0.02 [0.0–31.05] 0.688
Coriobacteriaceae Uncl. Coriobacteriaceae 0.09 [0.0–0.75] 0.04 [0.0–1.21] 0.342
Adlercreutzia 0.05 [0.0–0.12] 0.02 [0.0–0.21] 0.141
Collinsella 3.05 [0.24–18.62] 2. 80 [0.0–12.24] 0.262
Slackia 0.05 [0.0–0.35] 0.08 [0.0–1.56] 0.431
Bacteroidetes     24.40 [0.05–56.30]  4.48 [0.01–71.26]  0.115
Bacteroidaceae Bacteroides 0.63 [0.0–29.94] 0.96 [0.0–43.68] 0.774
Prevotellaceae Prevotella 9.71 [0.02–50.82] 1.27 [0.0–47.79] 0.075
[Paraprevotellaceae] [Prevotella] 0.10 [0.0–7.75] 0.02 [0.0–23.98] 0.885
Firmicutes     63.66 [20.84–95.03]  65.32 [21.71–97.00]   0.342
Enterococcaceae Enterococcus 0.06 [0.0–12.57] 0.08 [0.0–47.67] 0.7
Turicibacteraceae Turicibacter 0.0 [0.0–3.51] 0.01 [0.0–48.24] 0.142
Streptococcaceae Streptococcus 0.01 [0.0–10.00] 0.02 [0.0–49.65] 0.179
Uncl. Clostridiales Uncl. Clostridiales 0.07 [0.0–0.62] 0.21 [0.0–5.64] 0.071
Clostridiaceae Clostridium 5.55 [0.86–57.11] 7.26 [0.04–59.92] 0.888
Lachnospiraceae Uncl. Lachnospiraceae 3.58 [0.93–40.76] 3.59 [0.01–25.73] 0.822
Blautia 5.50 [2.01–27.11] 8.11 [0.0–38.68] 0.806
Clostridium 0.02 [0.0–8.11] 0.04 [0.0–5.48] 0.707
Coprococcus 0.13 [0.0–2.24] 0.19 [0.0–7.99] 0.378
Dorea 0.75 [0.0–3.31] 0.61 [0.0–9.00] 0.896
Roseburia 0.29 [0.0–2.92] 0.06 [0.0–18.42] 0.772
[Ruminococcus] 1.52 [0.19–9.28] 1.40 [0.0–9.57] 0.719
Peptococcaceae Peptococcus 0.43 [0.0–4.29] 0.93 [0.0–19.38] 0.241
Peptostreptococcaceae Uncl. Peptostreptococcaceae 0.52 [0.0–15.03] 0.37 [0.0–83.14] 0.637
Ruminococcaceae Uncl. Ruminococcaceae 0.70 [0.0–2.28] 1.05 [0.0–12.31] 0.407
Faecalibacterium 0.13 [0.0–2.43] 0.15 [0.0–9.64] 0.851
Oscillospira 0.13 [0.0–1.87] 0.28 [0.0–1.90] 0.43
Ruminococcus 0.03 [0.0–0.27] 0.03 [0.0–6.41] 0.975
Veillonellaceae Dialister 0.16 [0.0–3.03] 0.03 [0.0–4.11] 0.327
Megamonas 1.52 [0.0–17.31] 0.03 [0.0–7.39] 0.001*** 
Megasphaera 1.37 [0.0–14.27] 0.11 [0.0–15.54] 0.116
Phascolarctobacterium 0.30 [0.0–3.15] 0.03 [0.0–7.32] 0.42
[Mogibacteriaceae] Uncl. [Mogibacteriaceae] 0.22 [0.0–6.54] 0.09 [0.0–2.55] 0.325
Erysipelotrichaceae Bulleidia 0.04 [0.0–4.07] 0.09 [0.0–9.59] 0.974
Catenibacterium 0.44 [0.0–7.25] 0.09 [0.0–5.46] 0.121
[Eubacterium] 0.83 [0.02–8.04] 0.60 [0.0–11.56] 0.855
Fusobacteria     0.59 [0.01–25.95]  2.08 [0.0–50.63]   0.251
Uncl. Fusobacteriaceae Uncl. Fusobacteriaceae 0.59 [0.0–24.24] 1.52 [0.0–28.00] 0.507
Fusobacteriaceae Fusobacterium 0.0 [0.0–0.91] 0.03 [0.0–6.99] 0.334
Proteobacteria     6.40 [0.33–26.37] 3.18 [0.0–37.26] 0.306 
Alcaligenaceae Sutterella 0.34 [0.0–2.96] 0.59 [0.0–5.88] 0.389
Campylobacteraceae Campylobacter 0.06 [0.0–3.96] 0.01 [0.0–15.88] 0.050*
Succinivibrionaceae Anaerobiospirillum 1.62 [0.0–11.27] 0.01 [0.0–23.51] 0.046*
Enterobacteriaceae Uncl. Enterobacteriaceae 0.01 [0.0–2.34] 0.05 [0.0–22.12] 0.264
Helicobacteraceae Helicobacter 0.09 [0.0–5.13] 0.0 [0.0–5.25] 0.003**

*p<0.05 and

***p<0.001.

†Benjamini-Hochberg corrected p-value <0.15.