Table 2.

Synovial fluid amino acid concentrations by HPLC. Values (μm) are average (range) for each diagnosis.

Diagnosis	Glu	Asp	Gln*	Ser	Gly	Arg	Ctn	Thr
RA	326 (4–608)	38 (1–107)	201 (4–721)	109 (5–226)	261 (4–791)	112 (3–384)	37 (4–88)	152 (11–292)
Gout	362 (70–663)	36 (8–86)	217 (0–539)	131 (53–295)	231 (108–408)	118 (18–405)	36 (13–128)	130 (48–264)
OA	266 (0–530)	21 (2–69)	206 (26–489)	72 (28–170)	232 (110–415)	110 (25–242)	34 (11–114)	114 (78–264)
Pseudogout	267 (139–463)	22 (6–37)	154 (4–257)	96 (92–101)	211 (179–251)	67 (39–96)	23 (15–31)	81 (72–87)
Reiter’s	495 (268–895)	50 (19–98)	94 (8–70)	168 (86–355)	310 (131–480)	138 (64–289)	35 (9–85)	151 (72–255)
Psoriatic arthritis	273 (136–459)	48 (39–56)	227 (88–459)	184 (123–250)	360 (206–558)	162 (128–223)	25 (13–35)	122 (90–162)
Infectious arthropathy	378 (166–556)	66 (15–264)	161 (2–480)	130 (41–176)	269 (147–460)	78 (7–156)	58 (11–228)	144 (60–348)
Joint trauma	211 (157–287)	42 (15–65)	426 (52–617)	129 (66–169)	481 (149–1098)	145 (23–376)	50 (14–127)	131 (82–165)
SLE	458 (52–1061)	67 (4–201)	148 (5–512)	165 (33–375)	468 (149–925)	209 (67–587)	27 (9–44)	91 (60–209)
Autopsy samples n = 14**	6.25 (0.82–22)	1.39 (0–7.64)	70.97 (37–116)	7.59 (2.89–19.4)	43 (20.94–86.74)	9 (5.3–13.96)	2 (0.63–3.83)	17 (10–30)

^*Gln (glutamine) is a precursor to glutamic acid (Glu).

^**SF obtained from human autopsy specimens without joint disease.