. Author manuscript; available in PMC: 2021 Feb 19.

Published in final edited form as: Neurochem Res. 2017 Mar 16;42(7):1904–1918. doi: 10.1007/s11064-017-2227-7

Table 3.

Effect of prototype compounds on spontaneous bursting of a mEC-HC slice derived from adult rats following KA-induced SE. Effective concentrations are listed where calculated (μM)

Cmpd ID	Generic name		In vitro Post-KA rat bursting slice
Cmpd ID	Generic name	ASP ID #	ID	SB rate: IC50 (uM)	SB duration: IC50 (uM)
A	Acetaminophen	490002	−	NC	NC
B	Carbamazepine	490003	+	N/A	N/A
D	Retigabine	490,005	+	N/A	N/A
G	N6-Cyclopentyladenosine	490,008	+	0.005	0.19
H	m-CPP	490,009	+	384	405
J	Valproic acid	490,010	−	NC	NC

NC IC50 not calculated; inactive at 100 uM screen concentration

N/A Activity observed but IC50 not presently reported (see [22])

(+) Effect observed at 100 uM screening concentration

(−) No effect observed at 100 uM screening concentration