Progestogen in COC | Relative risk of VTE compared to COC with levonorgestrel | Incidence (per 10 000 women per year of use) | Estimated number of new cases of VTE in Germany per year (around 6.8 million users) (15) |
---|---|---|---|
Non-users | – | 2 | 1360 |
Levonorgestrel | 1 | 5 – 7 | 3400 – 4760 |
Norgestimate/norethisterone | 1 | 5 – 7 | 3400 – 4760 |
Dienogest | 1.6 | 8 – 11 | 5440 – 7480 |
Gestodene/desogestrel/drospirenone | 1.5 – 2 | 9 – 12 | 6120 – 8160 |
Etonogestrel/norelgestromin | 1 – 2 | 6 – 12 | 4080 – 8160 |
Chlormadinone/nomogestrol acetate + E2 | unknown | unknown | unknown |