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. 2021 Feb 8;47(4):45. doi: 10.3892/ijmm.2021.4878

Figure 4.

Figure 4

Effect of curcumin on the expression and activation of NRF2/ARE pathways in PM2.5-exposed cells. (A) Expression of NRF2 in the cytoplasm and nucleus. (B) Expression of KEAP1, HO-1, and NOQ-1. (C) Activation of ARE was evaluated by luciferase assay. Data are presented as the means ± SD; n=3, *P<0.05, **P<0.01 and ***P<0.001. PM2.5, fine particulate matter; NRF2, nuclear factor erythroid 2-related factor 2; ARE, antioxidant response element.