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. 2020 Oct 21;121(3):351–360. doi: 10.1055/s-0040-1717114

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The Author(s). This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial-License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. ( https://creativecommons.org/licenses/by-nc-nd/4.0/ ).

This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivatives License, which permits unrestricted reproduction and distribution, for non-commercial purposes only; and use and reproduction, but not distribution, of adapted material for non-commercial purposes only, provided the original work is properly cited.

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Fig. 1 — Trough plasma concentration of emicizumab (mean ± standard deviation) after 4 loading doses of 3 mg/kg once-weekly (QW) subcutaneous (SC) for 4 weeks, followed by maintenance dosing of 1.5 mg/kg QW SC. Means were derived from the values of participants of all emicizumab-treated arms ( n = 112). For patients in arm B ( n = 18) who switched to emicizumab prophylaxis after 24 weeks, scheduled time relative to first emicizumab dose was used for graphical displays.