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. 2020 Oct 21;121(3):351–360. doi: 10.1055/s-0040-1717114

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The Author(s). This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial-License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. ( https://creativecommons.org/licenses/by-nc-nd/4.0/ ).

This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivatives License, which permits unrestricted reproduction and distribution, for non-commercial purposes only; and use and reproduction, but not distribution, of adapted material for non-commercial purposes only, provided the original work is properly cited.

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Fig. 2 — Pharmacodynamic markers following once-weekly dosing with emicizumab. Chromogenic FVIII-like activity ( A ), peak height of thrombin generation (TG) ( B ), activated partial thromboplastin time (aPTT) ( C ), and prothrombin time (PT) ( D ). Dashed lines: individual profiles; red line: mean profile. ( n = 112 for FVIII-like activity and PT; n = 102 for TG and aPTT).