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. 2020 Oct 21;121(3):351–360. doi: 10.1055/s-0040-1717114

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The Author(s). This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial-License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. ( https://creativecommons.org/licenses/by-nc-nd/4.0/ ).

This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivatives License, which permits unrestricted reproduction and distribution, for non-commercial purposes only; and use and reproduction, but not distribution, of adapted material for non-commercial purposes only, provided the original work is properly cited.

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Fig. 4 — Pharmacokinetic/pharmacodynamic relationships. Correlation between emicizumab plasma concentrations and chromogenic FVIII-like activity ( A ), peak height of thrombin generation ( B ), activated partial thromboplastin time ( C ). ( A ) Gap at 10 U/dL reflects the use of two different calibration curves. ( C ) Line indicates model.