Table 3.

Residues in the first and second active sites.

Site No.	Residues
Site 1	Arg249, Leu251, Thr252, Ser255, Tyr265, Ile266, Trp268, Leu270, Val315, Leu316, Ser318, Thr319, Val320, Phe321, Pro322, Pro323, Thr324, Ser325, Phe326, Arg349, Glu350, Thr394, Cys395, Phe396, Tyr456, Arg457, Asn459, Leu460, Pro461, Thr462, Pro627, Asn628, Met629, Ser664, Val675, Pro677
Site 2	Val410, Lys411, His439, Phe440, Phe441, Phe442, Gln444, Asp452, Tyr455, Tyr456, Ala490, Asn491, Val493, Ile494, Val495, Asn496, Asn497, Leu498, Asp499, Lys500, Lys511, Arg513, Tyr516, Tyr521, Gln524, Met542, Leu544, Lys545, Tyr546,Ala547, Ile548, Ser549, Ala550, Lys551, Arg553, Ala554, Arg555, Thr556, Val557, Ala558, Lys577, Ala580, Ala581, Arg583, Gly590, Gly616, Trp617, Asp618, Tyr619, Pro620, Lys621, Cys622, Asp623, Arg624, Thr680, Ser681, Ser682, Thr687, Ala688, Asn691, Ser759, Asp760, Asp761, Ala762, Lys798, Trp800, His810, Glu811, Phe812, Cys813, Ser814, Gln815, Pro832, Asp833, Arg836, Ala840, Val844, Asp845, Lys849, Arg858