Table 2.
Contrast-to-noise ratio (CNR), signal-to-noise ratio (SNR) and quantitative bias (based on Eq. 9) (± standard deviation) calculated against the unfiltered (OSEM) PET images in the clinical studies
| CNR | SNR | Lesion SUVmean (Std. Dev.) | Lung SUVmean (Std. Dev.) | Liver SUVmean (Std. Dev.) | Bias (%) (for lesions) | |
|---|---|---|---|---|---|---|
| OSEM | 13.2 ± 3.7 | 23.3 ± 6.8 | 7.8 ± 2.0 (1.6) | 0.29 ± 0.08 (0.098) | 2.99 ± 0.8 (0.32) | – |
| Gaussian | 14.9 ± 3.6 | 26.5 ± 5.5 | 6.6 ± 1.9 (1.0) | 0.25 ± 0.07 (0.075) | 2.80 ± 0.7 (0.27) | − 12.3 ± 2.3 |
| Bilateral | 18.9 ± 4.1 | 29.2 ± 5.9 | 6.8 ± 1.9 (1.1) | 0.25 ± 0.06 (0.077) | 2.89 ± 0.7 (0.26) | − 7.7 ± 2.1 |
| NLM | 23.4 ± 4.4 | 32.4 ± 5.5 | 7.1 ± 1.7 (0.8) | 0.26 ± 0.05 (0.052) | 2.90 ± 0.7 (0.22) | − 3.5 ± 1.3 |
| MR-NLM | 25.0 ± 4.0 | 34.9 ± 5.7 | 7.3 ± 1.6 (0.7) | 0.27 ± 0.04 (0.050) | 2.94 ± 0.6 (0.19) | − 2.2 ± 1.2 |
| p value | 0.01 | 0.02 | 0.03 | 0.05 | 0.04 | 0.02 |
Mean SUV estimated in the liver, lung, and malignant lesions within these regions are also reported