Fig. 4.

Significant cluster 1 associated with clinical outcome. a), b) c) Higher electric field in the blue areas is associated with less optimal outcome in patients treated with bilateral (BL) ECT (MNI coordinates of peak: −57, 7, −11). The cluster is in the left temporal lobe including parts of the inferior and superior longitudinal fasciculus, inferior temporal gyrus and superior temporal gyrus. d) Scatter plot showing the mean electric field strength of the significant cluster and the end-MADRS-scores, corrected for covariates (for visualization purposes). The higher the electric field in this cluster, the higher was the MADRS-score after treatment. (For interpretation of the references to color in this figure legend, the reader is referred to the web version of this article.)