Table 3.
Annual per-person all-cause healthcare costa comparisons for porphyria patients during the 12 months before versus the 12 months after first diagnosis date, 2011–2014
| Healthcare costa ($US) | Pre-diagnosis (n = 2788) | Post-diagnosis (n = 2788) | p valueb |
|---|---|---|---|
| Total cost | |||
| Mean (SD) | 21,308 (52,775) | 27,370 (70,674) | < 0.0001 |
| Median [25th, 75th percentile] | 6497 (2360, 18,298) | 7842 (3041, 21,997) | |
| Inpatient admissions | |||
| Mean (SD) | 7400 (39,244) | 8882 (43,876) | 0.0020 |
| Median [25th, 75th percentile] | 0 (0, 0) | 0 (0, 0) | |
| Emergency department visits | |||
| Mean (SD) | 1370 (7082) | 1396 (5950) | 0.8863 |
| Median [25th, 75th percentile] | 0 (0, 263) | 0 (0, 0) | |
| Outpatient visits | |||
| Mean (SD) | 9459 (22,834) | 12,378 (41,774) | < 0.0001 |
| Median [25th, 75th percentile] | 3740 (1390, 9522) | 4241 (1662, 10,581) | |
| Pharmaceutical claims | |||
| Mean (SD) | 3079 (8728) | 4714 (15,672) | < 0.0001 |
| Median [25th, 75th percentile] | 559 (11, 2742) | 718 (24, 3153) |
SD standard deviation
aAll costs were adjusted to the 2019 United States Dollar (US$) using the medical care component of the Consumer Price Index
bWilcoxon signed rank test for cost differences before and after first porphyria diagnosis