Table 3.
Clinical outcomes of ICSI cycles using the spermatozoa from men harboring hemizygous CFAP47 variants
| Subject | T115 II-1 | T176 II-1 | H025 II-1 | MA2603 II-1 |
|---|---|---|---|---|
| Male age (years) | 37 | 26 | 34 | 31 |
| Female age (years) | 41 | 26 | 32 | N/A |
| Number of ICSI cycles | 1 | 1 | 1 | 1 |
| Number of oocytes injected | 1 | 9 | 11 | 12 |
| Number (and rate) of fertilized oocytes | 0 (0%) | 8 (89%) | 9 (82%) | 10 (83%) |
| Number (and rate) of cleavage embryos | ‒ | 8 (100%) | 9 (100%) | N/A |
| Number (and rate) of 8-cells | ‒ | 5 (63%) | 7 (78%) | N/A |
| Number (and rate) of blastocysts | ‒ | 5 (63%) | 7 (78%) | 3 (30%) |
| Number of transfer cycles | ‒ | 1 | 1 | 3 |
| Number of embryos transferred per cycle | ‒ | 2 | 2 | 1 |
| Implantation rate | ‒ | 100% | 50% | 66% |
| Clinical pregnancy rate | ‒ | 100% | 100% | 100% |
| Miscarriage rate | ‒ | 0% | 0% | 33% |
‒, not applicable; N/A, not available.