Figure 5.

Mutation of SALL4 ZFC4 causes embryonic lethality

(A) Table showing the number of live pups and embryos at different stages of development and their associated genotype. Animals were crossed to obtain ZFC4mut heterozygous (Het), homozygous (Hom), or WT progeny.

(B) Diagram showing the results from crossing ZFC4mut heterozygote mice. ZFC4mut homozygous animals die during embryonic development.

(C) Representative images of WT, ZFC4mut heterozygous (Het), and homozygous (Hom) embryos at E10.5, taken at the same magnification.

See also Figure S5.