Table 1.

Linear correlations (r) between age and metabolites; unpaired t-test (t) between sex and metabolites; unpaired t-test (t) between fasting state and metabolites.

	Homocysteine		Vitamin B12		Folate		Uric acid		Creatinine
Age	r	p	r	p	r	p	r	p	r	p
	0.467*	< 0.001*	− 0.253	0.002*	− 0.109	0.196	0.535*	< 0.001*	0.800**	< 0.001*
Sex (M/F)	t	p	t	p	t	p	t	p	t	p
	− 1.493	0.138	0.846	0.393	0.976	0.331	− 1.153	0.251	− 0.518	0.605
Fasting (yes/no)	t	p	t	p	t	p	t	p	t	p
	1.194	0.234	− 2.730	0.007*	− 1.190	0.236	2.227	0.028*	1.870	0.064

The analysis includes outliers. Further analysis after outlier exclusion is described in the text.

*p-value ≤ 0.05 or moderate correlation 0.4 < r < 0.7.

**Strong correlation with r ≥ 0.7.