Figure 5.

Cancellation versus stimulation of Ca²⁺ responses for different interphase intervals of a 2-ns bipolar pulse. (a) Results are plotted as the averaged fluorescence traces for cells exposed to a 2-ns unipolar pulse or a 2-ns bipolar pulse with various interphase delays (data from different panels of Fig. 4). (b) Peak amplitudes of Ca²⁺ transients with respect to unipolar exposure peak ± SEM (n = 18 for the unipolar pulse, n = 9, 7, 8, 4, and 6 cells for bipolar pulses with 0-, 10-, 30-, 60-, and 120-ns interphase intervals, respectively). Cumulative results including additional experiments are summarized in Table 1 and provided in Fig. S3. To see this figure in color, go online.