(a) (I) A membrane with an Ω-shape. The color bar represents the initial protein density (S,t = 0). (II) The budded region has a radius of curvature Rc, and the point at which the radial distance is minimal, SΩ, defines the budded area Abud. For the Ω-shape, ϕmax = 5π/6. (b) (I) A dome shape and the initial protein density is shown. (II) The dome region has a radius of curvature Rc and ϕmax = π/3. The dome area is given by the area of a spherical cap, Abud = (1 − cos(ϕmax)). (c) A pearled structure with two buds and the initial protein density is shown. (II) Each bud on the pearl has a radius of curvature Rc and ϕmax = 9π/10. The neck region has a radius of curvature Rneck. The area of the pearled structure is Abud = A(Spearl), at which the radial distance is minimal. (d) (I) A tube with the initial protein density is shown. (II) The tube has a radius Rt and a height Ltube measured from the bottom of the spherical cap to the tube rim. Stube = πRc/2 + Ltube, and the tube area is Abud = A(Stube). Initially, the total protein density mtot is the same for all shapes, and it is located at the top of the budding structures. The shapes are axially symmetric and represent shapes commonly observed in biological membranes. To see this figure in color, go online.