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. 2021 Jan 14;120(4):711–724. doi: 10.1016/j.bpj.2021.01.002

Figure 9.

Figure 9

Schematic correlation of data indicating the hypothesis of functional dependency of the chromatin reorganization and gene expression. The commitment of differentiation in MCF-7 cells after 15 min of HRG treatment. Unfolding of PADs under the critical threshold of silencing inducing critical acceleration of the whole-genome transcription is shown. Figure fragment for transcriptome data republished from (16) representing transcription speed change (nrmsf) of 22,277 genes shows the critical point at the 15 min of HRG treatment.