Figure 2.

Energy landscapes of a genetic toggle switch showcasing both steady-state behavior and intermediate dynamics. (A) Schematic of the genetic toggle switch is shown. (B) One-dimensional (1D) representations of the system landscape for different cooperativities of repression (top) with temporal trajectories of each cell for β = 2 and β = 3 (bottom) are shown. (C) Pseudoenergy landscapes are shown for different rates of production of A and B: (i) α_A = 1, α_B = 1, (ii) α_A = 3, α_B = 1, (iii) α_A = 1, α_B = 3, (iv) α_A = 3, α_B = 3. Color bar indicates system potential.