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. 2021 Feb 19;4:209. doi: 10.1038/s42003-021-01705-1

Fig. 4. Binding of Ac-p53 peptide to SIRT1 determined using ITC.

Fig. 4

a Titration of Ac-p53 peptide to the buffer for SIRT1 (183–510+GS+641–665). Binding of Ac-p53 peptide b to SIRT1 (183–510+GS+641–665), c to SIRT1 (183–510+GS+641–665) in the presence of 0.2 mM KPMF-8, and d to SIRT1 (183–510+GS+641–665) in the presence of 0.2 mM resveratrol. KD values ± curve-fit errors are indicated underneath each plot.