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. 2021 Feb 19;11:4271. doi: 10.1038/s41598-021-83906-6

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Cardiac ejection fractions (A), heart rates (B), left ventricle anterior wall dimensions (LWAVd) (C) and left ventricle posterior wall dimensions (LVPWd) (D) of control (CON), untreated heart failure (HF), ACE inhibitor-treated (ACEi) and AT₁ receptor blocker-treated (ARB) HanSD and TGR rats 20 weeks after sham or ACF operation (5 weeks in HF TGR rats due to high mortality). Data presented as mean ± SD (n = 10 in each group). ^#P < 0.05 compared to HanSD rats.